A gastrooesophagealis reflux betegség és az obstruktív alvási apnoe kapcsolata

Translated title of the contribution: The connection between gastroesophageal reflux disease and obstructive sleep apnoea

Pál Demeter, Katalin Várdi Visy

Research output: Contribution to journalReview article

1 Citation (Scopus)

Abstract

Clinical knowledge on the gastroesophageal reflux disease has been increased with the subject of extragastrointestinal complications in the last decade. Because of cardiological, pulmonological, laryngeal and dental complications, an interdisciplinary approach is required. The non-cardiac chest pain, bronchial asthma, chronic bronchitis, chronic cough, posterior laryngitis and acidic damage of dental enamel are the most important complications. Authors study a less common connection between the gastroesophageal reflux disease and obstructive sleep apnoea. Sleeping can be considered as a risk factor of the reflux event by itself, because of the decrease of primary peristalsis, producing of saliva, and acidic and volume clearance of oesophagus as well. During obstructive sleep apnoea negative intrathoracic pressure increases extremely, resulting in increased transdiaphragmatic gradient of pressure as well. In addition, the powerful movement of diaphragm twitches the lower oesophageal sphincter through the phrenoesophageal ligament. These two mechanism practically promotes the reflux event in patients with obstructive sleep apnea. The new challenge for the gastroenterologists is to further research this new connection, to play more active role in the complex therapy, and to have a new diagnostic approach of serious gastroesophageal reflux disease.

Original languageHungarian
Pages (from-to)439-444
Number of pages6
JournalLege Artis Medicinae
Volume13
Issue number6
Publication statusPublished - Sep 1 2003

    Fingerprint

ASJC Scopus subject areas

  • Medicine(all)

Cite this