The comparative value of the aortic atherosclerosis and the coronary flow velocity reverse evaluated by stress transesophageal echocardiography in the prediction of patients with aortic stenosis with coronary artery disease

Attila Nemes, T. Forster, A. Thury, Zsolt Kovács, K. Boda, M. Csanády

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Background: The present study was conducted to examine whether it is possible to differentiate patients with aortic stenosis (AOS) with or without significant stenosis of the left anterior descending coronary artery (LAD) on the basis of the age, gender, hypertension, diabetes mellitus, hypercholesterolemia, the coronary flow velocity reserve (CFVR) and the grade of aortic atherosclerosis (AA) evaluated by TEE in the course of the same semi-invasive examination. Patients and methods: Thirty-nine consecutive AOS patients who had undergone coronary angiography were examined by dipyridamole stress TEE to assess the CFVR. From this patient population, 21 AOS patients with anatomically normal coronary arteries (group 1), and 18 AOS patients with >75% stenosis of the LAD (group 2) were selected for the present study. The CFVR was calculated as the ratio of the average peak diastolic flow velocity (APV) during hyperemia to the resting APV. The grade of AA in the descending aorta was determined by means of the same TEE examination. Results: The demographic, clinical and transthoracic echocardiographic data, the coronary flow velocities and the CFVRs were similar in the two patient groups. Only the grade of AA (ROC area, 73%, p <0.02) appears useful for the distinction of AOS patients with or without significant LAD stenosis. Conclusions: These results demonstrate that only the grade of AA furnishes additional help in the prediction of AOS patients with severe LAD disease. CFVR has no any diagnostic power in the differentiation of AOS patients with or without significant LAD stenosis.

Original languageEnglish
Pages (from-to)371-376
Number of pages6
JournalInternational Journal of Cardiovascular Imaging
Volume19
Issue number5
DOIs
Publication statusPublished - Oct 2003

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Stress Echocardiography
Transesophageal Echocardiography
Aortic Valve Stenosis
Coronary Artery Disease
Atherosclerosis
Pathologic Constriction
Coronary Vessels
Dipyridamole
Hyperemia
Hypercholesterolemia
Coronary Angiography
Thoracic Aorta
Diabetes Mellitus
Demography
Hypertension

Keywords

  • Aortic atherosclerosis
  • Aortic valve stenosis
  • Coronary artery disease
  • Coronary flow
  • Transesophageal echocardiography

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine
  • Radiological and Ultrasound Technology

Cite this

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title = "The comparative value of the aortic atherosclerosis and the coronary flow velocity reverse evaluated by stress transesophageal echocardiography in the prediction of patients with aortic stenosis with coronary artery disease",
abstract = "Background: The present study was conducted to examine whether it is possible to differentiate patients with aortic stenosis (AOS) with or without significant stenosis of the left anterior descending coronary artery (LAD) on the basis of the age, gender, hypertension, diabetes mellitus, hypercholesterolemia, the coronary flow velocity reserve (CFVR) and the grade of aortic atherosclerosis (AA) evaluated by TEE in the course of the same semi-invasive examination. Patients and methods: Thirty-nine consecutive AOS patients who had undergone coronary angiography were examined by dipyridamole stress TEE to assess the CFVR. From this patient population, 21 AOS patients with anatomically normal coronary arteries (group 1), and 18 AOS patients with >75{\%} stenosis of the LAD (group 2) were selected for the present study. The CFVR was calculated as the ratio of the average peak diastolic flow velocity (APV) during hyperemia to the resting APV. The grade of AA in the descending aorta was determined by means of the same TEE examination. Results: The demographic, clinical and transthoracic echocardiographic data, the coronary flow velocities and the CFVRs were similar in the two patient groups. Only the grade of AA (ROC area, 73{\%}, p <0.02) appears useful for the distinction of AOS patients with or without significant LAD stenosis. Conclusions: These results demonstrate that only the grade of AA furnishes additional help in the prediction of AOS patients with severe LAD disease. CFVR has no any diagnostic power in the differentiation of AOS patients with or without significant LAD stenosis.",
keywords = "Aortic atherosclerosis, Aortic valve stenosis, Coronary artery disease, Coronary flow, Transesophageal echocardiography",
author = "Attila Nemes and T. Forster and A. Thury and Zsolt Kov{\'a}cs and K. Boda and M. Csan{\'a}dy",
year = "2003",
month = "10",
doi = "10.1023/A:1025829925910",
language = "English",
volume = "19",
pages = "371--376",
journal = "International Journal of Cardiovascular Imaging",
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T1 - The comparative value of the aortic atherosclerosis and the coronary flow velocity reverse evaluated by stress transesophageal echocardiography in the prediction of patients with aortic stenosis with coronary artery disease

AU - Nemes, Attila

AU - Forster, T.

AU - Thury, A.

AU - Kovács, Zsolt

AU - Boda, K.

AU - Csanády, M.

PY - 2003/10

Y1 - 2003/10

N2 - Background: The present study was conducted to examine whether it is possible to differentiate patients with aortic stenosis (AOS) with or without significant stenosis of the left anterior descending coronary artery (LAD) on the basis of the age, gender, hypertension, diabetes mellitus, hypercholesterolemia, the coronary flow velocity reserve (CFVR) and the grade of aortic atherosclerosis (AA) evaluated by TEE in the course of the same semi-invasive examination. Patients and methods: Thirty-nine consecutive AOS patients who had undergone coronary angiography were examined by dipyridamole stress TEE to assess the CFVR. From this patient population, 21 AOS patients with anatomically normal coronary arteries (group 1), and 18 AOS patients with >75% stenosis of the LAD (group 2) were selected for the present study. The CFVR was calculated as the ratio of the average peak diastolic flow velocity (APV) during hyperemia to the resting APV. The grade of AA in the descending aorta was determined by means of the same TEE examination. Results: The demographic, clinical and transthoracic echocardiographic data, the coronary flow velocities and the CFVRs were similar in the two patient groups. Only the grade of AA (ROC area, 73%, p <0.02) appears useful for the distinction of AOS patients with or without significant LAD stenosis. Conclusions: These results demonstrate that only the grade of AA furnishes additional help in the prediction of AOS patients with severe LAD disease. CFVR has no any diagnostic power in the differentiation of AOS patients with or without significant LAD stenosis.

AB - Background: The present study was conducted to examine whether it is possible to differentiate patients with aortic stenosis (AOS) with or without significant stenosis of the left anterior descending coronary artery (LAD) on the basis of the age, gender, hypertension, diabetes mellitus, hypercholesterolemia, the coronary flow velocity reserve (CFVR) and the grade of aortic atherosclerosis (AA) evaluated by TEE in the course of the same semi-invasive examination. Patients and methods: Thirty-nine consecutive AOS patients who had undergone coronary angiography were examined by dipyridamole stress TEE to assess the CFVR. From this patient population, 21 AOS patients with anatomically normal coronary arteries (group 1), and 18 AOS patients with >75% stenosis of the LAD (group 2) were selected for the present study. The CFVR was calculated as the ratio of the average peak diastolic flow velocity (APV) during hyperemia to the resting APV. The grade of AA in the descending aorta was determined by means of the same TEE examination. Results: The demographic, clinical and transthoracic echocardiographic data, the coronary flow velocities and the CFVRs were similar in the two patient groups. Only the grade of AA (ROC area, 73%, p <0.02) appears useful for the distinction of AOS patients with or without significant LAD stenosis. Conclusions: These results demonstrate that only the grade of AA furnishes additional help in the prediction of AOS patients with severe LAD disease. CFVR has no any diagnostic power in the differentiation of AOS patients with or without significant LAD stenosis.

KW - Aortic atherosclerosis

KW - Aortic valve stenosis

KW - Coronary artery disease

KW - Coronary flow

KW - Transesophageal echocardiography

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U2 - 10.1023/A:1025829925910

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JO - International Journal of Cardiovascular Imaging

JF - International Journal of Cardiovascular Imaging

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