The brain tumor is the most frequent solid tumor in childhood. Its incidence was 4,4/100 000 in Hungary in 1998. The therapy consists of surgical, radio- and chemotherapy. However, the most important prognostic factor is the surgical resection of the tumor followed by irradiation in children older than 3 years. Chemotherapy is indicated only in chemosensitive tumors. The most chemosensitive tumors are: the medulloblastomas, primitiv neuroectodermal tumors (PNET), germ cell tumors and the intracranial lymphomas. The optimal chemotherapy is not defined yet because of the several contradictory data and observations based on a low number of patients. This paper describes the present indications of chemotherapy, the most effective drugs and drug-combinations in the treatment of brain tumors, the expected results and the chemotherapy of medulloblastoma/PNET applied by Hungarian Pediatric Oncology Group.
|Translated title of the contribution||The chemotherapy of brain tumors|
|Number of pages||6|
|Publication status||Published - Jan 1 2001|
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