The authors report their experiences in detection of prostate cancer at serum prostate specific antigen level lower than 4 ng/ml. They examined the ratio of significant cancers in 82 patients who had transrectal ultrasound guided fine needle prostate biopsy and in 17 patients who underwent radical perineal prostatectomy. 17 of 82 (21%) patients proved to be positive in the biopsy and 1 of 17 patients had significant cancer. 2 of 10 patients who had organ confined disease in the radical perineal prostatectomy had significant cancer (Gleason score 8-10). In the group of patients with locally advanced disease 1 patient had a well (Gleason score 3), three patients had a moderately (Gleason score 5-7), while two patients had poorly differentiated tumors. The authors emphasize that the 4 ng/ml serum prostate specific antigen level is an acceptable threshold and using age specific reference ranges we can eliminate the great number of unnecessary biopsies without missing significant prostate cancers.
|Translated title of the contribution||The characteristics of prostate cancer detected at serum prostate specific antigen level lower than 4 ng/ml. Evaluations of data of our patients in our department|
|Number of pages||6|
|Publication status||Published - Dec 1 2005|
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