A lichen szájüregi vonatkozásai. Osszefoglaló referátum.

Translated title of the contribution: [The characteristics of oral lichen planus].

Sandor Bogdán, Z. Németh

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Lichen is a chronic, mucocutan disease with unknown origin. Oral lesions are usually bilateral, the most frequent location of the reticular form is the posterior part of the buccal mucosa. It undergo only rarely spontaneous remission, and it has a potential to turn into malignant tumor. It is hypothesized that due to an antigen-specific mechanism, auto-cytotoxic T-cells infiltrates the affected region. T-lymphocytes induces apoptosis in the keratinocytes of the basal epithelium. Since etiology is unknown, there is no cure for lichen. The symptomatic treatment has been focused on reducing the subjective discomfort and to maintain or improve the quality of life. The main course of therapy are topical retinoids, locally given steroids, but immunosuppressive therapies have been also tried. Data about exact etiology, diagnostical criteria and effective treatment are still limited. Therefore, besides the early detection of the disease, symptomatic treatment, and the close observation of dysplastic lesions is recommended.

Original languageHungarian
Pages (from-to)35-42
Number of pages8
JournalFogorvosi szemle
Volume105
Issue number1
Publication statusPublished - Mar 2012

Fingerprint

Oral Lichen Planus
Lichens
Spontaneous Remission
T-Lymphocytes
Retinoids
Mouth Mucosa
Immunosuppressive Agents
Keratinocytes
Early Diagnosis
Chronic Disease
Epithelium
Steroids
Quality of Life
Observation
Apoptosis
Antigens
Therapeutics
Neoplasms

ASJC Scopus subject areas

  • Medicine(all)

Cite this

A lichen szájüregi vonatkozásai. Osszefoglaló referátum. / Bogdán, Sandor; Németh, Z.

In: Fogorvosi szemle, Vol. 105, No. 1, 03.2012, p. 35-42.

Research output: Contribution to journalArticle

@article{afbaef3f1a9645ccb431fc73aaa44a77,
title = "A lichen sz{\'a}j{\"u}regi vonatkoz{\'a}sai. Osszefoglal{\'o} refer{\'a}tum.",
abstract = "Lichen is a chronic, mucocutan disease with unknown origin. Oral lesions are usually bilateral, the most frequent location of the reticular form is the posterior part of the buccal mucosa. It undergo only rarely spontaneous remission, and it has a potential to turn into malignant tumor. It is hypothesized that due to an antigen-specific mechanism, auto-cytotoxic T-cells infiltrates the affected region. T-lymphocytes induces apoptosis in the keratinocytes of the basal epithelium. Since etiology is unknown, there is no cure for lichen. The symptomatic treatment has been focused on reducing the subjective discomfort and to maintain or improve the quality of life. The main course of therapy are topical retinoids, locally given steroids, but immunosuppressive therapies have been also tried. Data about exact etiology, diagnostical criteria and effective treatment are still limited. Therefore, besides the early detection of the disease, symptomatic treatment, and the close observation of dysplastic lesions is recommended.",
author = "Sandor Bogd{\'a}n and Z. N{\'e}meth",
year = "2012",
month = "3",
language = "Hungarian",
volume = "105",
pages = "35--42",
journal = "Fogorvosi szemle",
issn = "0015-5314",
publisher = "Ifjusagi Lapkiado Vallalat",
number = "1",

}

TY - JOUR

T1 - A lichen szájüregi vonatkozásai. Osszefoglaló referátum.

AU - Bogdán, Sandor

AU - Németh, Z.

PY - 2012/3

Y1 - 2012/3

N2 - Lichen is a chronic, mucocutan disease with unknown origin. Oral lesions are usually bilateral, the most frequent location of the reticular form is the posterior part of the buccal mucosa. It undergo only rarely spontaneous remission, and it has a potential to turn into malignant tumor. It is hypothesized that due to an antigen-specific mechanism, auto-cytotoxic T-cells infiltrates the affected region. T-lymphocytes induces apoptosis in the keratinocytes of the basal epithelium. Since etiology is unknown, there is no cure for lichen. The symptomatic treatment has been focused on reducing the subjective discomfort and to maintain or improve the quality of life. The main course of therapy are topical retinoids, locally given steroids, but immunosuppressive therapies have been also tried. Data about exact etiology, diagnostical criteria and effective treatment are still limited. Therefore, besides the early detection of the disease, symptomatic treatment, and the close observation of dysplastic lesions is recommended.

AB - Lichen is a chronic, mucocutan disease with unknown origin. Oral lesions are usually bilateral, the most frequent location of the reticular form is the posterior part of the buccal mucosa. It undergo only rarely spontaneous remission, and it has a potential to turn into malignant tumor. It is hypothesized that due to an antigen-specific mechanism, auto-cytotoxic T-cells infiltrates the affected region. T-lymphocytes induces apoptosis in the keratinocytes of the basal epithelium. Since etiology is unknown, there is no cure for lichen. The symptomatic treatment has been focused on reducing the subjective discomfort and to maintain or improve the quality of life. The main course of therapy are topical retinoids, locally given steroids, but immunosuppressive therapies have been also tried. Data about exact etiology, diagnostical criteria and effective treatment are still limited. Therefore, besides the early detection of the disease, symptomatic treatment, and the close observation of dysplastic lesions is recommended.

UR - http://www.scopus.com/inward/record.url?scp=84861137015&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84861137015&partnerID=8YFLogxK

M3 - Article

C2 - 22530368

AN - SCOPUS:84861137015

VL - 105

SP - 35

EP - 42

JO - Fogorvosi szemle

JF - Fogorvosi szemle

SN - 0015-5314

IS - 1

ER -