The change of the ground substance of the aorta in syphilitic aortitis

L. Józsa, Gy Szederkényi, G. Lusztig

Research output: Contribution to journalArticle


The authors reviewed the changes of mucopolysaccharides in 14 cases of syphilitic aortitis. The results are as follows: 1. The hyaluronic acid and heparin-heparitin content decreases and chondroitinsulphate accumulates in the aortic wall. 2. The mucopolysaccharides deposited in the aorta are markedly depolymerised and the molecular weight of certain fractions is considerably lower than in other pathological conditions. The changes in quantity and polymerism of mucopolysaccharides differ from those observed in other conditions and are "specific" for syphilitic aortitis.

Original languageEnglish
Pages (from-to)324-330
Number of pages7
JournalVirchows Archiv A Pathologische Anatomie
Issue number4
Publication statusPublished - Dec 1 1968

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

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