The morphology of C cells of the thyroid was investigated in rats from newborn to 18 months of age. While in the newborn rat thyroid the C cells do not exhibit argyrophilia and metachromasia, a gradually increasing reactivity can be noted from 10 to 30 days of age. From 30 days to 18 months of age the cells are highly reactive. At the age of 30 days the C cells increase in size; this is particularly conspicuous at 30 and 50 days of age. The C cells are mainly localized parafollicularly, in the central part of the glandular lobe, their number decreasing towards the periphery. The ultimobranchial follicles enlarge gradually after 20 days, they do not exhibit argyrophilia and metachromasia, but a few C cells showing marked argyrophilic and metachromatic reaction are constantly present in the vicinity of the ultimobranchial follicles.
|Number of pages||9|
|Journal||Acta morphologica Academiae Scientiarum Hungaricae|
|Publication status||Published - Dec 1 1974|
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