The bridge between TLC and HPLC

Overpressured layer chromatography (OPLC)

Research output: Contribution to journalArticle

43 Citations (Scopus)

Abstract

An account of the basic principle of overpressured layer chromatography (OPLC) is given, followed by a description of the commercially available instrument, operating and development modes, as well as special techniques and how to eliminate typical problems arising during the use of OPLC. A comparison of fully off-line and on-line OPLC separations and the correlation between OPLC and HPLC retention data are summarized. Although this article is not intended as a comprehensive review, reference is made to a number of papers and reviews enabling the reader to acquire a deeper knowledge of the topic.

Original languageEnglish
Pages (from-to)91-101
Number of pages11
JournalTrAC - Trends in Analytical Chemistry
Volume20
Issue number2
DOIs
Publication statusPublished - 2001

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Chromatography

Keywords

  • Development modes
  • Mobile phase transfer
  • Off-line mode
  • On-line mode
  • Overpressured layer chromatography (OPLC)

ASJC Scopus subject areas

  • Analytical Chemistry

Cite this

The bridge between TLC and HPLC : Overpressured layer chromatography (OPLC). / Nyiredy, S.

In: TrAC - Trends in Analytical Chemistry, Vol. 20, No. 2, 2001, p. 91-101.

Research output: Contribution to journalArticle

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