The binding of125i-tsh to thyroid cell receptors previously deformed (In neonatal age) by gonadotropin treatment

G. Csaba, Susanna U. Nagy

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Single gonadotropin treatment of newborn rats caused a 63-71% decrease of TSH-binding on isolated thyroid cells prepared from thyroid glands of both 6- and 13-month-old animals. This fact points out that: (1) in newborn animals the hormone receptors are still plastic and deformable and (2) the damaging effect of the analogous hormone manifests itself at the receptor level.

Original languageEnglish
Pages (from-to)275-277
Number of pages3
JournalNeonatology
Volume34
Issue number5-6
DOIs
Publication statusPublished - 1978

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Keywords

  • Gonadotropin
  • Receptor deformation
  • Receptor development
  • TSH

ASJC Scopus subject areas

  • Developmental Biology
  • Pediatrics, Perinatology, and Child Health

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