The binding of amino acids to the herbicide 2,4-dichlorophenoxy acetic acid

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

The interaction of amino acids with the herbicide 2,4-dichlorophenoxyacetic acid (2,4-D) was studied by charge-transfer chromatography carried out on diatomaceous layers covered with different amount of 2,4-D and the effect of salts on the strength of interaction was elucidated. It was established that Arg, His, Lys, Orn, Phe and Trp binds to 2,4-D, the binding process is of saturation character. Principal component analysis proved that the concentration of 2,4-D exerts the highest impact on the interaction and the effect of salts is of secondary importance. The results suggest that these amino acid residues may account for the binding of 2,4-D to proteins and can play a considerable role in the detoxification processes by forming conjugates with 2,4-D.

Original languageEnglish
Pages (from-to)69-79
Number of pages11
JournalAmino Acids
Volume18
Issue number1
Publication statusPublished - 2000

Fingerprint

2,4-Dichlorophenoxyacetic Acid
Herbicides
Amino Acids
Salts
Detoxification
Chromatography
Principal Component Analysis
Principal component analysis
Charge transfer

Keywords

  • 2,4-Dichlorophenoxyacetic acid
  • Amino acids
  • Charge-transfer chromatography
  • Polar interaction

ASJC Scopus subject areas

  • Clinical Biochemistry
  • Biochemistry
  • Endocrinology

Cite this

The binding of amino acids to the herbicide 2,4-dichlorophenoxy acetic acid. / Forgács, E.; Cserháti, T.; Barta, I.

In: Amino Acids, Vol. 18, No. 1, 2000, p. 69-79.

Research output: Contribution to journalArticle

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