The base-catalyzed oxygenation of quinoline derivatives

Miklós Czaun, G. Speier

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

The base-catalyzed oxygenation of 1H-2-phenyl-3-hydroxy-4-oxoquinoline leads to cleavage products derived from either an endoperoxide or a 1,2-dioxetan intermediate. A persistent 1H-2-phenyl-3-oxy-4-oxoquinoline radical could also be detected by EPR in the reaction mixture.

Original languageEnglish
Pages (from-to)5961-5963
Number of pages3
JournalTetrahedron Letters
Volume43
Issue number34
DOIs
Publication statusPublished - Aug 19 2002

Fingerprint

4-Quinolones
Oxygenation
Derivatives
Paramagnetic resonance
quinoline

Keywords

  • 1,2-dioxetan
  • Base-catalysis
  • Dioxygenation
  • Endoperoxide
  • Quinoline

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

The base-catalyzed oxygenation of quinoline derivatives. / Czaun, Miklós; Speier, G.

In: Tetrahedron Letters, Vol. 43, No. 34, 19.08.2002, p. 5961-5963.

Research output: Contribution to journalArticle

Czaun, Miklós ; Speier, G. / The base-catalyzed oxygenation of quinoline derivatives. In: Tetrahedron Letters. 2002 ; Vol. 43, No. 34. pp. 5961-5963.
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