The azaphilic addition of organometallic reagents on tetrazines: Scope and limitations

János Faragó, Zoltán Novák, Gitta Schlosser, Antal Csámpai, András Kotschy

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22 Citations (Scopus)

Abstract

A series of tetrazines were reacted with organometallic reagents. Depending on the nature of the metal azaphilic addition, reduction of the tetrazine or simple complex formation was the predominant transformation and usually high selectivity was observed.

Original languageEnglish
Pages (from-to)1991-1996
Number of pages6
JournalTetrahedron
Volume60
Issue number9
DOIs
Publication statusPublished - Feb 23 2004

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Keywords

  • Aromatic nucleophilic substitution
  • Azaphilic addition
  • Reduction
  • Tetrazines

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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