A várandós no parodontalis egészségi állapota és a terhességi komplikációk közötti kapcsolat

Translated title of the contribution: The association between maternal periodontal health and adverse pregnancy outcomes

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Data from epidemiological and clinical studies published in the past two decades indicate certain association between periodontal disease and increased risk for preterm birth or low birth weight. Although the strength of those observed associations is weak, periodontitis today is considered as one of the potentially modifiable risk factors for adverse pregnancy outcomes. The aims of the publication are to summarize the epidemiological and clinical evidence for the impact of periodontal disease on adverse pregnancy outcomes and to make an attempt to overview the potential biological mechanism behind this association. The majority of epidemiological and clinical studies found certain negative effect of poor maternal periodontal condition on the incidence of low birth weight, preterm birth, pre-eclampsy, restricted foetal growth or even stillbirth. Two possible biological pathways have so far been identified: 1) the direct dissemination of the periodontal pathogens or their toxic by-products which reach the foetal-placental unit, and 2) an indirect mechanism when the circulating systemic inflammatory mediators induced by the periodontal inflammation can provoke secondary inflammation and foetal damage in the amnion. The periodontal therapy applied during the second or third trimesters has not been proven to reduce the incidence of any adverse pregnancy outcomes in pregnant women. A much more prophylaxis-oriented approach in periodontal treatment is needed. The adequate periodontal therapy should be completed before the conception to provide benefit to the pregnant women and also the new born baby.

Original languageHungarian
Pages (from-to)999-1007
Number of pages9
JournalOrvosi Hetilap
Volume159
Issue number25
DOIs
Publication statusPublished - Jun 1 2018

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Pregnancy Outcome
Premature Birth
Low Birth Weight Infant
Periodontal Diseases
Pregnant Women
Epidemiologic Studies
Inflammation
Amnion
Stillbirth
Poisons
Periodontitis
Incidence
Third Pregnancy Trimester
Second Pregnancy Trimester
Fetal Development
Publications
Therapeutics
Mothers
Maternal Health
Clinical Studies

ASJC Scopus subject areas

  • Medicine(all)

Cite this

A várandós no parodontalis egészségi állapota és a terhességi komplikációk közötti kapcsolat. / Gera, I.

In: Orvosi Hetilap, Vol. 159, No. 25, 01.06.2018, p. 999-1007.

Research output: Contribution to journalArticle

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