The ascorbate-glutathione-α-tocopherol triad in abiotic stress response

A. Szarka, Bálint Tomasskovics, G. Bánhegyi

Research output: Contribution to journalArticle

101 Citations (Scopus)

Abstract

The life of any living organism can be defined as a hurdle due to different kind of stresses. As with all living organisms, plants are exposed to various abiotic stresses, such as drought, salinity, extreme temperatures and chemical toxicity. These primary stresses are often interconnected, and lead to the overproduction of reactive oxygen species (ROS) in plants, which are highly reactive and toxic and cause damage to proteins, lipids, carbohydrates and DNA, which ultimately results in oxidative stress. Stress-induced ROS accumulation is counteracted by enzymatic antioxidant systems and non-enzymatic low molecular weight metabolites, such as ascorbate, glutathione and α-tocopherol. The above mentioned low molecular weight antioxidants are also capable of chelating metal ions, reducing thus their catalytic activity to form ROS and also scavenge them. Hence, in plant cells, this triad of low molecular weight antioxidants (ascorbate, glutathione and α-tocopherol) form an important part of abiotic stress response. In this work we are presenting a review of abiotic stress responses connected to these antioxidants.

Original languageEnglish
Pages (from-to)4458-4483
Number of pages26
JournalInternational Journal of Molecular Sciences
Volume13
Issue number4
DOIs
Publication statusPublished - Apr 2012

Fingerprint

tocopherol
glutathione
Tocopherols
Antioxidants
Glutathione
Reactive Oxygen Species
antioxidants
Molecular Weight
Molecular weight
low molecular weights
Oxygen
Oxidative stress
Poisons
Drought
Droughts
organisms
Salinity
Plant Cells
Carbohydrates
Metabolites

Keywords

  • α-tocopherol
  • Abiotic stress
  • Ascorbate
  • Glutathione
  • Oxidative stress

ASJC Scopus subject areas

  • Computer Science Applications
  • Molecular Biology
  • Catalysis
  • Inorganic Chemistry
  • Spectroscopy
  • Organic Chemistry
  • Physical and Theoretical Chemistry
  • Medicine(all)

Cite this

The ascorbate-glutathione-α-tocopherol triad in abiotic stress response. / Szarka, A.; Tomasskovics, Bálint; Bánhegyi, G.

In: International Journal of Molecular Sciences, Vol. 13, No. 4, 04.2012, p. 4458-4483.

Research output: Contribution to journalArticle

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