The acute phase reaction syndrome: The acute phase reactants: (A Review)

L. Jakab, L. Kalabay

Research output: Contribution to journalReview article

23 Citations (Scopus)

Abstract

The acute phase reaction of the organism, which determines the response that follows the injury of tissues and organs and helps the survival of the individual is reviewed. The main participants, the induction of the reaction and the regulatory mechanisms are shortly discussed, with special respect to the prominent role of interleukin-6. The relationship between the production and synthesis of the acute phase reactants under physiological and pathophysiological conditions is analyzed. The particular functions of orosomucoid and α2HS-glycoprotein are summarized. Finally, the common biological actions of IL-6 and the acute phase reactants are mentioned.

Original languageEnglish
Pages (from-to)409-418
Number of pages10
JournalActa microbiologica et immunologica Hungarica
Volume45
Issue number3-4
Publication statusPublished - Dec 1 1998

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ASJC Scopus subject areas

  • Immunology and Microbiology(all)

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