TGF-beta 1 and IL-6--new aspects in pancreas regeneration?

G. Farkas, T. Takács, Y. Mándi, A. Balogh

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2 Citations (Scopus)


Plasma levels of interleukin-6 (IL-6) and transforming growth factor-beta (TGF-beta 1) were studied during cholecystokinin octapeptide (CCK-8)-induced regeneration after pancreas resection in rats. The weight of the pancreas and the DNA and protein contents increased significantly. The serum levels of TGF-beta 1 and IL-6 were increased significantly on days 7 and 14. There was no significant change in serum amylase levels. These findings indicate that cytokines such as TGF-beta 1 and IL-6 may play a role in the pathomechanism of pancreas regeneration.

Original languageEnglish
Pages (from-to)89-91
Number of pages3
JournalActa Chirurgica Hungarica
Issue number1-4
Publication statusPublished - 1997


ASJC Scopus subject areas

  • Surgery

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