Terminal sequences of the bacteriophage ϕ6 segmented dsRNA genome and its messenger RNAs

Miklos Szekeres, Bernard H. Brownstein, Helen R. Revel, Robert Haselkorn

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11 Citations (Scopus)

Abstract

The ends of the three dsRNA genome segments (L, M, and S) of bacteriophage φ{symbol}6 (strand separated and/or intact) and the 5′ ends of the middle and small single-strand messenger RNAs have been sequenced by base-specific partial enzymatic digestion. Terminal sequences for the large and middle dsRNA strands extend about 60 bases. The three dsRNA segments have 18 homologous bases at the left end except for position 2, which differs in the L segment. A 17-base homology defines the right ends of L and M dsRNAs and probably S dsRNA as well. The 5′ ends of middle and small messenger RNAs are identical to the corresponding viral (+) strands.

Original languageEnglish
Pages (from-to)1-11
Number of pages11
JournalVirology
Volume142
Issue number1
DOIs
Publication statusPublished - Apr 15 1985

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ASJC Scopus subject areas

  • Virology

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