Temperature sensitivity of some nerve conduction parameters in diabetic polyneuropathy

Eszter Hidasi, Péter Diószeghy, Miklós Káplár, Ferenc Mechler, D. Bereczki

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Background - We tested whether in diabetic polyneuropathy the temperature dependence of the median nerve conduction parameters reflects the severity of neuropathy. Methods - We validated an electrophysiological score against clinical signs of polyneuropathy. Electroneurography was performed at temperatures from 20-40°C in diabetic patients with mild, moderate and severe neuropathy and controls. Results - The electrophysiological score reflected the clinical severity of polyneuropathy. At room temperature there were significant differences among groups in almost all parameters. In thermal sensitivity studies were significant differences in distal and proximal motor and sensory areas and in sensory conduction velocities. These four parameters normalized to 1°C change in temperature also significantly differed among the four groups and were largest in controls and smallest in severe polyneuropathy. Conclusions - The use of an integral parameter - areas are essentially amplitudes integrated over time - increases the probability of detecting decreased thermal sensitivity of peripheral nerves in diabetes.

Original languageEnglish
Pages (from-to)178-186
Number of pages9
JournalIdeggyógyászati szemle
Volume67
Issue number5-6
Publication statusPublished - May 30 2014

Fingerprint

Diabetic Neuropathies
Neural Conduction
Polyneuropathies
Temperature
Hot Temperature
Median Nerve
Peripheral Nerves

Keywords

  • Diabetes
  • Electroneurography
  • Neuropathy
  • Scoring
  • Temperature

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology

Cite this

Hidasi, E., Diószeghy, P., Káplár, M., Mechler, F., & Bereczki, D. (2014). Temperature sensitivity of some nerve conduction parameters in diabetic polyneuropathy. Ideggyógyászati szemle, 67(5-6), 178-186.

Temperature sensitivity of some nerve conduction parameters in diabetic polyneuropathy. / Hidasi, Eszter; Diószeghy, Péter; Káplár, Miklós; Mechler, Ferenc; Bereczki, D.

In: Ideggyógyászati szemle, Vol. 67, No. 5-6, 30.05.2014, p. 178-186.

Research output: Contribution to journalArticle

Hidasi, E, Diószeghy, P, Káplár, M, Mechler, F & Bereczki, D 2014, 'Temperature sensitivity of some nerve conduction parameters in diabetic polyneuropathy', Ideggyógyászati szemle, vol. 67, no. 5-6, pp. 178-186.
Hidasi, Eszter ; Diószeghy, Péter ; Káplár, Miklós ; Mechler, Ferenc ; Bereczki, D. / Temperature sensitivity of some nerve conduction parameters in diabetic polyneuropathy. In: Ideggyógyászati szemle. 2014 ; Vol. 67, No. 5-6. pp. 178-186.
@article{9d44adb795454393af7983d6c81dd520,
title = "Temperature sensitivity of some nerve conduction parameters in diabetic polyneuropathy",
abstract = "Background - We tested whether in diabetic polyneuropathy the temperature dependence of the median nerve conduction parameters reflects the severity of neuropathy. Methods - We validated an electrophysiological score against clinical signs of polyneuropathy. Electroneurography was performed at temperatures from 20-40°C in diabetic patients with mild, moderate and severe neuropathy and controls. Results - The electrophysiological score reflected the clinical severity of polyneuropathy. At room temperature there were significant differences among groups in almost all parameters. In thermal sensitivity studies were significant differences in distal and proximal motor and sensory areas and in sensory conduction velocities. These four parameters normalized to 1°C change in temperature also significantly differed among the four groups and were largest in controls and smallest in severe polyneuropathy. Conclusions - The use of an integral parameter - areas are essentially amplitudes integrated over time - increases the probability of detecting decreased thermal sensitivity of peripheral nerves in diabetes.",
keywords = "Diabetes, Electroneurography, Neuropathy, Scoring, Temperature",
author = "Eszter Hidasi and P{\'e}ter Di{\'o}szeghy and Mikl{\'o}s K{\'a}pl{\'a}r and Ferenc Mechler and D. Bereczki",
year = "2014",
month = "5",
day = "30",
language = "English",
volume = "67",
pages = "178--186",
journal = "Ideggyogyaszati Szemle",
issn = "0019-1442",
publisher = "Ifjusagi Lap-es Konyvkiado Vallalat",
number = "5-6",

}

TY - JOUR

T1 - Temperature sensitivity of some nerve conduction parameters in diabetic polyneuropathy

AU - Hidasi, Eszter

AU - Diószeghy, Péter

AU - Káplár, Miklós

AU - Mechler, Ferenc

AU - Bereczki, D.

PY - 2014/5/30

Y1 - 2014/5/30

N2 - Background - We tested whether in diabetic polyneuropathy the temperature dependence of the median nerve conduction parameters reflects the severity of neuropathy. Methods - We validated an electrophysiological score against clinical signs of polyneuropathy. Electroneurography was performed at temperatures from 20-40°C in diabetic patients with mild, moderate and severe neuropathy and controls. Results - The electrophysiological score reflected the clinical severity of polyneuropathy. At room temperature there were significant differences among groups in almost all parameters. In thermal sensitivity studies were significant differences in distal and proximal motor and sensory areas and in sensory conduction velocities. These four parameters normalized to 1°C change in temperature also significantly differed among the four groups and were largest in controls and smallest in severe polyneuropathy. Conclusions - The use of an integral parameter - areas are essentially amplitudes integrated over time - increases the probability of detecting decreased thermal sensitivity of peripheral nerves in diabetes.

AB - Background - We tested whether in diabetic polyneuropathy the temperature dependence of the median nerve conduction parameters reflects the severity of neuropathy. Methods - We validated an electrophysiological score against clinical signs of polyneuropathy. Electroneurography was performed at temperatures from 20-40°C in diabetic patients with mild, moderate and severe neuropathy and controls. Results - The electrophysiological score reflected the clinical severity of polyneuropathy. At room temperature there were significant differences among groups in almost all parameters. In thermal sensitivity studies were significant differences in distal and proximal motor and sensory areas and in sensory conduction velocities. These four parameters normalized to 1°C change in temperature also significantly differed among the four groups and were largest in controls and smallest in severe polyneuropathy. Conclusions - The use of an integral parameter - areas are essentially amplitudes integrated over time - increases the probability of detecting decreased thermal sensitivity of peripheral nerves in diabetes.

KW - Diabetes

KW - Electroneurography

KW - Neuropathy

KW - Scoring

KW - Temperature

UR - http://www.scopus.com/inward/record.url?scp=84903215493&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84903215493&partnerID=8YFLogxK

M3 - Article

VL - 67

SP - 178

EP - 186

JO - Ideggyogyaszati Szemle

JF - Ideggyogyaszati Szemle

SN - 0019-1442

IS - 5-6

ER -