Tc-99m HMPAO leukocyte and Tc-99m nanocolloid scintigraphy in posttraumatic bone infection

Miklós Papós, Ferenc Barát, György Nárai, József Dillmann, Jenö Láng, L. Csernay

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Posttraumatic osteomyelitis was investigated in 23 patients using nuclear medicine techniques. Tc-99m hexamethylpropilene amine oxime (HMPAO)- labeled leukocyte scintigraphy was performed in 11 patients, and Tc-99m, nanocolloid scanning was performed in the other 12 patients. The scintigraphic findings were compared with clinical, laboratory, radiologic, and bacteriologic results. The findings on leukocyte imaging were consistent with the clinical symptoms in 7 of 11 patients, with the laboratory pattern in 7 of 10 patients, with the radiologic findings in 7 of 11 patients, and with the results of bacteriology in 6 of 7 patients. The findings on nanocolloid scintigraphy corresponded with the clinical symptoms in 9 of 12 patients, with the laboratory pattern in 8 of 10 patients, with the radiologic findings in 8 of 12 patients, and with the bacteriology in 4 of 5 patients. The results suggest that both methods were of similar value for the detection of chronic posttraumatic osteomyelitis regardless of whether the process was active. Conversely, on the basis of semiquantitative analysis of the images, leukocyte scintigraphy seemed to characterize the grade of inflammation better than did nanocolloid scintigraphy.

Original languageEnglish
Pages (from-to)423-428
Number of pages6
JournalClinical Nuclear Medicine
Volume23
Issue number7
DOIs
Publication statusPublished - Jul 1998

Fingerprint

Oximes
Radionuclide Imaging
Amines
Leukocytes
Bone and Bones
Infection
Bacteriology
Osteomyelitis
technetium Tc 99m nanocolloid
Nuclear Medicine
Inflammation

Keywords

  • Leukocyte Scintigraphy
  • Nanocolloid Scintigraphy
  • Posttraumatic Osteomyelitis
  • Semiquantitative analysis of Images

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Tc-99m HMPAO leukocyte and Tc-99m nanocolloid scintigraphy in posttraumatic bone infection. / Papós, Miklós; Barát, Ferenc; Nárai, György; Dillmann, József; Láng, Jenö; Csernay, L.

In: Clinical Nuclear Medicine, Vol. 23, No. 7, 07.1998, p. 423-428.

Research output: Contribution to journalArticle

Papós, Miklós ; Barát, Ferenc ; Nárai, György ; Dillmann, József ; Láng, Jenö ; Csernay, L. / Tc-99m HMPAO leukocyte and Tc-99m nanocolloid scintigraphy in posttraumatic bone infection. In: Clinical Nuclear Medicine. 1998 ; Vol. 23, No. 7. pp. 423-428.
@article{af4a136f474743e0bd7fbf79817c90d7,
title = "Tc-99m HMPAO leukocyte and Tc-99m nanocolloid scintigraphy in posttraumatic bone infection",
abstract = "Posttraumatic osteomyelitis was investigated in 23 patients using nuclear medicine techniques. Tc-99m hexamethylpropilene amine oxime (HMPAO)- labeled leukocyte scintigraphy was performed in 11 patients, and Tc-99m, nanocolloid scanning was performed in the other 12 patients. The scintigraphic findings were compared with clinical, laboratory, radiologic, and bacteriologic results. The findings on leukocyte imaging were consistent with the clinical symptoms in 7 of 11 patients, with the laboratory pattern in 7 of 10 patients, with the radiologic findings in 7 of 11 patients, and with the results of bacteriology in 6 of 7 patients. The findings on nanocolloid scintigraphy corresponded with the clinical symptoms in 9 of 12 patients, with the laboratory pattern in 8 of 10 patients, with the radiologic findings in 8 of 12 patients, and with the bacteriology in 4 of 5 patients. The results suggest that both methods were of similar value for the detection of chronic posttraumatic osteomyelitis regardless of whether the process was active. Conversely, on the basis of semiquantitative analysis of the images, leukocyte scintigraphy seemed to characterize the grade of inflammation better than did nanocolloid scintigraphy.",
keywords = "Leukocyte Scintigraphy, Nanocolloid Scintigraphy, Posttraumatic Osteomyelitis, Semiquantitative analysis of Images",
author = "Mikl{\'o}s Pap{\'o}s and Ferenc Bar{\'a}t and Gy{\"o}rgy N{\'a}rai and J{\'o}zsef Dillmann and Jen{\"o} L{\'a}ng and L. Csernay",
year = "1998",
month = "7",
doi = "10.1097/00003072-199807000-00005",
language = "English",
volume = "23",
pages = "423--428",
journal = "Clinical Nuclear Medicine",
issn = "0363-9762",
publisher = "Lippincott Williams and Wilkins",
number = "7",

}

TY - JOUR

T1 - Tc-99m HMPAO leukocyte and Tc-99m nanocolloid scintigraphy in posttraumatic bone infection

AU - Papós, Miklós

AU - Barát, Ferenc

AU - Nárai, György

AU - Dillmann, József

AU - Láng, Jenö

AU - Csernay, L.

PY - 1998/7

Y1 - 1998/7

N2 - Posttraumatic osteomyelitis was investigated in 23 patients using nuclear medicine techniques. Tc-99m hexamethylpropilene amine oxime (HMPAO)- labeled leukocyte scintigraphy was performed in 11 patients, and Tc-99m, nanocolloid scanning was performed in the other 12 patients. The scintigraphic findings were compared with clinical, laboratory, radiologic, and bacteriologic results. The findings on leukocyte imaging were consistent with the clinical symptoms in 7 of 11 patients, with the laboratory pattern in 7 of 10 patients, with the radiologic findings in 7 of 11 patients, and with the results of bacteriology in 6 of 7 patients. The findings on nanocolloid scintigraphy corresponded with the clinical symptoms in 9 of 12 patients, with the laboratory pattern in 8 of 10 patients, with the radiologic findings in 8 of 12 patients, and with the bacteriology in 4 of 5 patients. The results suggest that both methods were of similar value for the detection of chronic posttraumatic osteomyelitis regardless of whether the process was active. Conversely, on the basis of semiquantitative analysis of the images, leukocyte scintigraphy seemed to characterize the grade of inflammation better than did nanocolloid scintigraphy.

AB - Posttraumatic osteomyelitis was investigated in 23 patients using nuclear medicine techniques. Tc-99m hexamethylpropilene amine oxime (HMPAO)- labeled leukocyte scintigraphy was performed in 11 patients, and Tc-99m, nanocolloid scanning was performed in the other 12 patients. The scintigraphic findings were compared with clinical, laboratory, radiologic, and bacteriologic results. The findings on leukocyte imaging were consistent with the clinical symptoms in 7 of 11 patients, with the laboratory pattern in 7 of 10 patients, with the radiologic findings in 7 of 11 patients, and with the results of bacteriology in 6 of 7 patients. The findings on nanocolloid scintigraphy corresponded with the clinical symptoms in 9 of 12 patients, with the laboratory pattern in 8 of 10 patients, with the radiologic findings in 8 of 12 patients, and with the bacteriology in 4 of 5 patients. The results suggest that both methods were of similar value for the detection of chronic posttraumatic osteomyelitis regardless of whether the process was active. Conversely, on the basis of semiquantitative analysis of the images, leukocyte scintigraphy seemed to characterize the grade of inflammation better than did nanocolloid scintigraphy.

KW - Leukocyte Scintigraphy

KW - Nanocolloid Scintigraphy

KW - Posttraumatic Osteomyelitis

KW - Semiquantitative analysis of Images

UR - http://www.scopus.com/inward/record.url?scp=0031663099&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0031663099&partnerID=8YFLogxK

U2 - 10.1097/00003072-199807000-00005

DO - 10.1097/00003072-199807000-00005

M3 - Article

C2 - 9676945

AN - SCOPUS:0031663099

VL - 23

SP - 423

EP - 428

JO - Clinical Nuclear Medicine

JF - Clinical Nuclear Medicine

SN - 0363-9762

IS - 7

ER -