Taurine Levels in Discrete Brain Nuclei of Rats

Miklós Palkovits; István Elekes; Tibor Láng; András Patthy

doi:10.1111/j.1471-4159.1986.tb00761.x

Taurine Levels in Discrete Brain Nuclei of Rats

Miklós Palkovits, István Elekes, Tibor Láng, András Patthy

Semmelweis University

Research output: Contribution to journal › Article

86 Citations (Scopus)

Abstract

Abstract Concentrations of taurine have been measured in 44 microdissected rat brain nuclei or areas. Taurine is ubiquitously present and distributed unevenly in the rat brain: the ratio of the highest (pyriform cortex) to lowest (midbrain reticular formation) concentrations is 4.7:1. High taurine levels were found in cerebral cortical areas, caudate‐puta‐men, cerebellum, median eminence, and supraoptic nucleus. Acute pain stress reduced taurine levels in the hypothalamus and the lower brainstem nuclei but not in cortical areas. Increased locomotor and behavioral activities following a high dose of amphetamine elevated taurine concentrations significantly in the substantia nigra and locus ceruleus.

Original language	English
Pages (from-to)	1333-1335
Number of pages	3
Journal	Journal of neurochemistry
Volume	47
Issue number	5
DOIs	https://doi.org/10.1111/j.1471-4159.1986.tb00761.x
Publication status	Published - Nov 1986

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Keywords

Amphetamine
Pain stress
Rat brain nuclei
Taurine

ASJC Scopus subject areas

Biochemistry
Cellular and Molecular Neuroscience

Cite this

Palkovits, M., Elekes, I., Láng, T., & Patthy, A. (1986). Taurine Levels in Discrete Brain Nuclei of Rats. Journal of neurochemistry, 47(5), 1333-1335. https://doi.org/10.1111/j.1471-4159.1986.tb00761.x

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10.1111/j.1471-4159.1986.tb00761.x