Abstract
Abstract Concentrations of taurine have been measured in 44 microdissected rat brain nuclei or areas. Taurine is ubiquitously present and distributed unevenly in the rat brain: the ratio of the highest (pyriform cortex) to lowest (midbrain reticular formation) concentrations is 4.7:1. High taurine levels were found in cerebral cortical areas, caudate‐puta‐men, cerebellum, median eminence, and supraoptic nucleus. Acute pain stress reduced taurine levels in the hypothalamus and the lower brainstem nuclei but not in cortical areas. Increased locomotor and behavioral activities following a high dose of amphetamine elevated taurine concentrations significantly in the substantia nigra and locus ceruleus.
| Original language | English |
|---|---|
| Pages (from-to) | 1333-1335 |
| Number of pages | 3 |
| Journal | Journal of neurochemistry |
| Volume | 47 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - Nov 1986 |
Keywords
- Amphetamine
- Pain stress
- Rat brain nuclei
- Taurine
ASJC Scopus subject areas
- Biochemistry
- Cellular and Molecular Neuroscience
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Cite this
Palkovits, M., Elekes, I., Láng, T., & Patthy, A. (1986). Taurine Levels in Discrete Brain Nuclei of Rats. Journal of neurochemistry, 47(5), 1333-1335. https://doi.org/10.1111/j.1471-4159.1986.tb00761.x