T3P®-mediated one-pot synthesis of Bis(α-aminophosphonates)

Mátyás Milen, Péter Ábrányi-Balogh, Réka Kangyal, András Dancsõ, Dávid Frigyes, György Keglevich

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13 Citations (Scopus)

Abstract

Two series of bis(α-aminophosphonates) were synthesized by one-pot three-component reactions using 4-phenylenediamine, an aldehyde (2 equiv) and a phosphite (2 equiv), or terephtalaldehyde, an amine (2 equiv), and a phosphite (2 equiv) together with propylphosphonic anhydride (T3P®) in both series as a coupling reagent. The bis(α-aminophosphonates) were obtained in moderate to excellent yields. The condensations take place under mild conditions and the isolation of the products is simple.

Original languageEnglish
Pages (from-to)245-255
Number of pages11
JournalHeteroatom Chemistry
Volume25
Issue number4
DOIs
Publication statusPublished - Jul 2014

ASJC Scopus subject areas

  • Chemistry(all)

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    Milen, M., Ábrányi-Balogh, P., Kangyal, R., Dancsõ, A., Frigyes, D., & Keglevich, G. (2014). T3P®-mediated one-pot synthesis of Bis(α-aminophosphonates). Heteroatom Chemistry, 25(4), 245-255. https://doi.org/10.1002/hc.21170