Szex szteroid-és hypophysishormonszintek prognosztikus jelento{double acute}sége fej-nyaki laphámrákban

E. Remenár, Számel Irén, Budai Barna, Orosz Zsolt, I. Gaudi, M. Kásler, S. Gundy

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Objective of the study: to investigate the clinical outcome of HNSCC patients, and their hormonal status. Method: The liver function (GGT), hypophysis gonadotrop hormone (FSH, LH, prolactin) and sexsteroid hormone serum levels were examined in 130 male HNSCC patients. Clinical parameters for age, primary tumor site and clinical tumor stage were also recorded. Results: The survival was disadvantageously influenced by the following parameters: age, the presence of lymph node metastasis, advanced tumor stage, the lower than normal testosterone and the higher than normal FSH serum levels. Conclusion: Elevated FSH and decreased testosterone serum levels showed significant correlation with the survival of head and neck cancer patients. The better understanding of their exact role in the biology of HNSCC requires further investigations.

Original languageHungarian
Pages (from-to)155-159
Number of pages5
JournalMagyar Onkologia
Volume47
Issue number2
Publication statusPublished - 2003

ASJC Scopus subject areas

  • Oncology

Cite this

Szex szteroid-és hypophysishormonszintek prognosztikus jelento{double acute}sége fej-nyaki laphámrákban. / Remenár, E.; Irén, Számel; Barna, Budai; Zsolt, Orosz; Gaudi, I.; Kásler, M.; Gundy, S.

In: Magyar Onkologia, Vol. 47, No. 2, 2003, p. 155-159.

Research output: Contribution to journalArticle

@article{e479fe72cfd545d592635854a37b8d89,
title = "Szex szteroid-{\'e}s hypophysishormonszintek prognosztikus jelento{double acute}s{\'e}ge fej-nyaki laph{\'a}mr{\'a}kban",
abstract = "Objective of the study: to investigate the clinical outcome of HNSCC patients, and their hormonal status. Method: The liver function (GGT), hypophysis gonadotrop hormone (FSH, LH, prolactin) and sexsteroid hormone serum levels were examined in 130 male HNSCC patients. Clinical parameters for age, primary tumor site and clinical tumor stage were also recorded. Results: The survival was disadvantageously influenced by the following parameters: age, the presence of lymph node metastasis, advanced tumor stage, the lower than normal testosterone and the higher than normal FSH serum levels. Conclusion: Elevated FSH and decreased testosterone serum levels showed significant correlation with the survival of head and neck cancer patients. The better understanding of their exact role in the biology of HNSCC requires further investigations.",
author = "E. Remen{\'a}r and Sz{\'a}mel Ir{\'e}n and Budai Barna and Orosz Zsolt and I. Gaudi and M. K{\'a}sler and S. Gundy",
year = "2003",
language = "Hungarian",
volume = "47",
pages = "155--159",
journal = "Magyar Onkologia",
issn = "0025-0244",
publisher = "Akademiai Kiado",
number = "2",

}

TY - JOUR

T1 - Szex szteroid-és hypophysishormonszintek prognosztikus jelento{double acute}sége fej-nyaki laphámrákban

AU - Remenár, E.

AU - Irén, Számel

AU - Barna, Budai

AU - Zsolt, Orosz

AU - Gaudi, I.

AU - Kásler, M.

AU - Gundy, S.

PY - 2003

Y1 - 2003

N2 - Objective of the study: to investigate the clinical outcome of HNSCC patients, and their hormonal status. Method: The liver function (GGT), hypophysis gonadotrop hormone (FSH, LH, prolactin) and sexsteroid hormone serum levels were examined in 130 male HNSCC patients. Clinical parameters for age, primary tumor site and clinical tumor stage were also recorded. Results: The survival was disadvantageously influenced by the following parameters: age, the presence of lymph node metastasis, advanced tumor stage, the lower than normal testosterone and the higher than normal FSH serum levels. Conclusion: Elevated FSH and decreased testosterone serum levels showed significant correlation with the survival of head and neck cancer patients. The better understanding of their exact role in the biology of HNSCC requires further investigations.

AB - Objective of the study: to investigate the clinical outcome of HNSCC patients, and their hormonal status. Method: The liver function (GGT), hypophysis gonadotrop hormone (FSH, LH, prolactin) and sexsteroid hormone serum levels were examined in 130 male HNSCC patients. Clinical parameters for age, primary tumor site and clinical tumor stage were also recorded. Results: The survival was disadvantageously influenced by the following parameters: age, the presence of lymph node metastasis, advanced tumor stage, the lower than normal testosterone and the higher than normal FSH serum levels. Conclusion: Elevated FSH and decreased testosterone serum levels showed significant correlation with the survival of head and neck cancer patients. The better understanding of their exact role in the biology of HNSCC requires further investigations.

UR - http://www.scopus.com/inward/record.url?scp=84875002882&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84875002882&partnerID=8YFLogxK

M3 - Article

VL - 47

SP - 155

EP - 159

JO - Magyar Onkologia

JF - Magyar Onkologia

SN - 0025-0244

IS - 2

ER -