Szisztémás sclerosis emlötumorban szenvedö betegnél

Translated title of the contribution: Systemic sclerosis in a patient suffering from breast cancer

Szabolcsi Orsolya, Nagy Toldi Annamária, M. Zeher, Végh Judit

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Scleroderma is the general disease of the connective tissue, which can be characterized by the proliferation of the connective tissue and fibrosis. According to the results of international studies scleroderma is frequently accompanied by neoplastic diseases, among which the most often occurring is the neoplastic pathology of the breast and the lungs. In May 2007, in the case of our 40-year-old woman patient the histological examination of the tumor we noticed in the left breast verified invasive carcinoma. In December 2007, after neoadjuvant chemotherapy she had a left mastectomy and then she was given postoperative irradiation, hormone therapy and trastuzumab (Herceptin) treatment, which was suspended in December 2008 due to oedema and fibrosis all over the body. In May 2009 she first visited the immunology outpatient department of our clinic, where we started her examination because of our suspicion of scleroderma and her cutaneous fibrosis symptoms, which was established on the basis of the examinations (immunoserology, body plethysmography, diffusing capacity of the lung for carbon monoxide, capillary microscopy, barium swallow) and her symptoms. She was given a conservative therapy (pentoxyphylline, amlodipine, nitroglycerin). Scleroderma arising after the neoplastic process of the breast is usually much more progressive than the primary disease. International reports also show a close correlation between breast cancer and the development of scleroderma, but its exact mechanism is not yet clear.

Original languageHungarian
Pages (from-to)50-54
Number of pages5
JournalMagyar Onkologia
Volume56
Issue number1
Publication statusPublished - 2012

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Systemic Scleroderma
Breast
Fibrosis
Breast Neoplasms
Lung Volume Measurements
Neoplastic Processes
Amlodipine
Connective Tissue Diseases
Plethysmography
Mastectomy
Nitroglycerin
Barium
Carbon Monoxide
Deglutition
Allergy and Immunology
Connective Tissue
Microscopy
Edema
Outpatients
Hormones

ASJC Scopus subject areas

  • Oncology

Cite this

Orsolya, S., Annamária, N. T., Zeher, M., & Judit, V. (2012). Szisztémás sclerosis emlötumorban szenvedö betegnél. Magyar Onkologia, 56(1), 50-54.

Szisztémás sclerosis emlötumorban szenvedö betegnél. / Orsolya, Szabolcsi; Annamária, Nagy Toldi; Zeher, M.; Judit, Végh.

In: Magyar Onkologia, Vol. 56, No. 1, 2012, p. 50-54.

Research output: Contribution to journalArticle

Orsolya, S, Annamária, NT, Zeher, M & Judit, V 2012, 'Szisztémás sclerosis emlötumorban szenvedö betegnél', Magyar Onkologia, vol. 56, no. 1, pp. 50-54.
Orsolya S, Annamária NT, Zeher M, Judit V. Szisztémás sclerosis emlötumorban szenvedö betegnél. Magyar Onkologia. 2012;56(1):50-54.
Orsolya, Szabolcsi ; Annamária, Nagy Toldi ; Zeher, M. ; Judit, Végh. / Szisztémás sclerosis emlötumorban szenvedö betegnél. In: Magyar Onkologia. 2012 ; Vol. 56, No. 1. pp. 50-54.
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