Syphilitic hepatitis: clinical, immunological and morphological aspects

J. Fehér, T. Somogyi, M. Timmer, L. Josza

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In 17 out of 176 cases of early syphilis (seropositive syphilis I; syphilis II) liver function tests yielded a positive result. In these patients a significant increase in the serum IgG, IgM and coeruloplasmin levels and a decrease in the transferrin level was found. The concentrations of α 2 macroglobulin and of β 1 C globulin were practically unaffected. Liver biopsy revealed hepatitis of variable severity in 13 patients with focal necroses or a proliferative process affecting the walls of the central veins, the arterioles and the branches of the portal vein. In 7 cases the presence of Treponema in the liver was demonstrated. (Journal received Nov. 1976).

Original languageEnglish
Pages (from-to)155-161
Number of pages7
JournalActa Medica Academiae Scientiarum Hungaricae
Issue number2
Publication statusPublished - 1975


ASJC Scopus subject areas

  • Medicine(all)

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