Synthetic studies to improve the deuterium labelling in nucleosides for facilitating structural studies of large RNAs by high-field NMR spectroscopy

M. K. Kundu, A. Trifonova, Z. Dinya, A. Földesi, J. Chattopadhyaya

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5 Citations (Scopus)

Abstract

Synthetic studies to prepare ribonucleosides deuterated at C2′ and the application of the developed procedures for the synthesis of 2H5-ribonucleosides from 1,2-O-isopropylidene-3-O-benzyl-ribofuranose-3,4,5,5′ -2H4 have been reported.

Original languageEnglish
Pages (from-to)1333-1337
Number of pages5
JournalNucleosides, Nucleotides and Nucleic Acids
Volume20
Issue number4-7
DOIs
Publication statusPublished - Sep 17 2001

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ASJC Scopus subject areas

  • Biochemistry
  • Molecular Medicine
  • Genetics

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