11C-kolin eloállítása szilá rdfázisú extrakciós technika alkalmazásával

Translated title of the contribution: Synthesis of11C-choline using the solid phase extraction technique

Tünde Miklovicz, Pál Mikecz, Géza Horváth, Lajos Trón, Teréz Márián

Research output: Contribution to journalArticle

Abstract

11C labelled choline was synthesized by two methods. The conventional method resulted in the product at 130 °C in 20 minutes while the solid phase extraction technique was carried out at room temperature in much less time. The quality control was carried out using HPLC method. As the first biological experiments the cellular uptake of 11C-choline was investigated in human cell lines. The effect of multidrug resistance on the uptake was also studied.

Original languageHungarian
Pages (from-to)329-333
Number of pages5
JournalMagyar Kemiai Folyoirat, Kemiai Kozlemenyek
Volume108
Issue number7
Publication statusPublished - Jul 1 2002

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ASJC Scopus subject areas

  • Chemistry(all)

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