Synthesis of vinca alkaloids and related compounds XXXV. Preparation of 1-ethyl-1-hydroxyethyl-octahydroindolo[2,3-a]quinolizine derivatives and reactions of their mesylates with cyanide ion

György Kalaus, Numan Malkieh, Mária Kajtár-Peredy, János Brlik, Lajos Szabó, Csaba Szántay

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Starting from (±)-eburnamonine (la) and (±)-3-epieburnamonine (lb), compounds 5 and 11 were prepared. The reaction of the mesylate of 5 or 11 with NaCN in DMF led to a mixture of 16 and 17. The structures of the new compounds were elucidated.

Original languageEnglish
Pages (from-to)1179-1190
Number of pages12
JournalHeterocycles
Volume27
Issue number5
DOIs
Publication statusPublished - May 1988

ASJC Scopus subject areas

  • Analytical Chemistry
  • Pharmacology
  • Organic Chemistry

Fingerprint Dive into the research topics of 'Synthesis of vinca alkaloids and related compounds XXXV. Preparation of 1-ethyl-1-hydroxyethyl-octahydroindolo[2,3-a]quinolizine derivatives and reactions of their mesylates with cyanide ion'. Together they form a unique fingerprint.

  • Cite this