Synthesis of vinca alkaloids and related compounds XLVIII synthesis of (+)-catharanthine and (±)-allocatharanthine

Csaba Szántay, Hedvig Bölcskei, Eszter Gács-Baitz

Research output: Contribution to journalArticle

39 Citations (Scopus)

Abstract

The first synthesis of natural (+)-catharanthine (ulbar>1) has been achieved in a few steps and in ∼20 % overall yield based on indole-3--acetic acid. The isomeric (±)-allocatharanthine was also prepared.

Original languageEnglish
Pages (from-to)1711-1732
Number of pages22
JournalTetrahedron
Volume46
Issue number5
DOIs
Publication statusPublished - 1990

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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