Synthesis of vinca alkaloids and related compounds part 94 [1]. Epimerization of compounds with aspidospermane and D-secoaspidospermane skeleton [section]

György Kalaus, Imre Juhász, János Éles, István Greiner, Mária Kajtár-Peredy, János Brlik, Lajos Szabó, Csaba Szántay

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9 Citations (Scopus)

Abstract

The individual epimerization steps of vincadifformine (1), deethylvincadifformine isomers (2,3), their synthetic intermediates (4-13) as well as that of simpler compounds with D-secoaspidospermane skeleton (1517) were studied a) in protic medium (boiling deuteroacetic acidic) and b) under reductive (with sodium borodeuteride in boiling acetic acid, or with sodium borohydride in boiling deuteroacetic acid) conditions.

Original languageEnglish
Pages (from-to)245-251
Number of pages7
JournalJournal of Heterocyclic Chemistry
Volume37
Issue number2
DOIs
Publication statusPublished - Jan 1 2000

ASJC Scopus subject areas

  • Organic Chemistry

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