Synthesis of the enantiomers and N-protected derivatives of 3-amino-3-(4-cyanophenyl)propanoic acid

Magdolna Solymár, Liisa T. Kanerva, Ferenc Fülöp

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Racemic ethyl 3-amino-3-(4-cyanophenyl)propanoate was synthesized and the enantiomers separated through enantioselective N-acylation by Candida antarctica lipase A (CAL-A) in neat butyl butanoate. The free amino acid enantiomers were transformed to the Boc and Fmoc-protected derivatives.

Original languageEnglish
Pages (from-to)1893-1897
Number of pages5
JournalTetrahedron Asymmetry
Volume15
Issue number12
DOIs
Publication statusPublished - Jun 21 2004

ASJC Scopus subject areas

  • Catalysis
  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry

Fingerprint Dive into the research topics of 'Synthesis of the enantiomers and N-protected derivatives of 3-amino-3-(4-cyanophenyl)propanoic acid'. Together they form a unique fingerprint.

  • Cite this