Synthesis of tachrosin, a natural flavone substituted by a novel furanoid ring system

Sándor Antus, Loránd Farkas, Mihály Nógrádi, Pál Sohár

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Tachrosin, 5,7-dimethoxy-8-( 2,3-dihydro-2,2-dimethyl-3-oxofuran-4-y1) flavone (1), was synthesised using the oxidative rearrangement of a 5-aryl-2-hydroxy-pent-4-en-3-one (2) with Tl(NO3)3 in methanol to a 4-aryl-5-methoxytetrahydrofuran-3-one (3) followed by elimination of the elements of methanol to form the dihydrofuranone ring.

Original languageEnglish
Pages (from-to)799a
JournalJournal of the Chemical Society, Chemical Communications
Issue number19
DOIs
Publication statusPublished - Jan 1 1974

ASJC Scopus subject areas

  • Molecular Medicine

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