Synthesis of some steroidal oxazolines

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Steroidal oxazolines 4a-4d and 5a-5f were synthesized. The acid-catalyzed reactions of 21-azido-20-hydroxy- and 21-hydroxy-20-azidosteroids with substituted aromatic aldehydes led to the formation of androst-5-en-3β-ols substituted in position 17β with oxazoline residues.

Original languageEnglish
Pages (from-to)1831-1840
Number of pages10
JournalCollection of Czechoslovak Chemical Communications
Volume66
Issue number12
Publication statusPublished - Dec 2001

Fingerprint

Aldehydes
Acids

Keywords

  • Oxazolines
  • Schmidt reaction
  • Steroids
  • Vicinal-azidoalcohols

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Synthesis of some steroidal oxazolines. / Wölfling, J.; Mernyák, E.; Sebõk, Melinda; Schneider, G.

In: Collection of Czechoslovak Chemical Communications, Vol. 66, No. 12, 12.2001, p. 1831-1840.

Research output: Contribution to journalArticle

@article{afd823b672bd43e9a0120f6334b14042,
title = "Synthesis of some steroidal oxazolines",
abstract = "Steroidal oxazolines 4a-4d and 5a-5f were synthesized. The acid-catalyzed reactions of 21-azido-20-hydroxy- and 21-hydroxy-20-azidosteroids with substituted aromatic aldehydes led to the formation of androst-5-en-3β-ols substituted in position 17β with oxazoline residues.",
keywords = "Oxazolines, Schmidt reaction, Steroids, Vicinal-azidoalcohols",
author = "J. W{\"o}lfling and E. Merny{\'a}k and Melinda Seb{\~o}k and G. Schneider",
year = "2001",
month = "12",
language = "English",
volume = "66",
pages = "1831--1840",
journal = "ChemPlusChem",
issn = "2192-6506",
publisher = "Wiley-VCH Verlag",
number = "12",

}

TY - JOUR

T1 - Synthesis of some steroidal oxazolines

AU - Wölfling, J.

AU - Mernyák, E.

AU - Sebõk, Melinda

AU - Schneider, G.

PY - 2001/12

Y1 - 2001/12

N2 - Steroidal oxazolines 4a-4d and 5a-5f were synthesized. The acid-catalyzed reactions of 21-azido-20-hydroxy- and 21-hydroxy-20-azidosteroids with substituted aromatic aldehydes led to the formation of androst-5-en-3β-ols substituted in position 17β with oxazoline residues.

AB - Steroidal oxazolines 4a-4d and 5a-5f were synthesized. The acid-catalyzed reactions of 21-azido-20-hydroxy- and 21-hydroxy-20-azidosteroids with substituted aromatic aldehydes led to the formation of androst-5-en-3β-ols substituted in position 17β with oxazoline residues.

KW - Oxazolines

KW - Schmidt reaction

KW - Steroids

KW - Vicinal-azidoalcohols

UR - http://www.scopus.com/inward/record.url?scp=31344470257&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=31344470257&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:31344470257

VL - 66

SP - 1831

EP - 1840

JO - ChemPlusChem

JF - ChemPlusChem

SN - 2192-6506

IS - 12

ER -