Synthesis of some novel D-ring-fused dioxa- and oxazaphosphorinanes in the estrone series

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Abstract

New types of P-heterocyclic-fused steroids, such as dioxa- and oxazaphosphorinane derivatives, were synthetized from estrone-1,3-dihydroxy and 1,3-aminoalcohol precursors by cyclization with phenylphosphonic dichloride.

Original languageEnglish
Pages (from-to)1105-1108
Number of pages4
JournalTetrahedron Letters
Volume47
Issue number7
DOIs
Publication statusPublished - Feb 13 2006

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Keywords

  • Dioxaphosphorinanes
  • Estrone derivatives
  • Oxazaphosphorinanes
  • Steroids

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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