Starting from the key intermediate 2 previously used for the preparation of derivatives with a normal yohimbane skeleton, the synthesis of rac‐deserpidine (1b) and the rac‐raunescine epimer 9c, having an epi‐allo and allo skeleton, respectively, has been performed. In the course of the synthesis several stereoisomers of C‐18‐substituted allo‐yohimbine have been prepared and characterized by spectroscopic and chemical means.
ASJC Scopus subject areas
- Physical and Theoretical Chemistry
- Organic Chemistry