Synthesis of pyrrolo[3,4-c]quinolines by 1,5-electrocyclisation of non-stabilised azomethine ylides

Miklós Nyerges, Áron Pintér, A. Virányi, Gábor Blaskó, L. Tőke

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

A new route to the pyrrolo[3,4-c]quinoline ring system has been developed via the 1,5-dipolar electrocyclisation reactions of azomethine ylides derived from easily available 3-formylquinoline derivatives. The intermediacy of azomethine ylides was shown by the trapping of the proposed dipoles with N-phenylmaleimide.

Original languageEnglish
Pages (from-to)8199-8205
Number of pages7
JournalTetrahedron
Volume61
Issue number34
DOIs
Publication statusPublished - Aug 22 2005

Fingerprint

Quinolines
Derivatives
azomethine
quinoline
N-phenylmaleimide

Keywords

  • Azomethine ylide
  • Cycloaddition
  • Electrocyclisation
  • Pyrroles

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

Synthesis of pyrrolo[3,4-c]quinolines by 1,5-electrocyclisation of non-stabilised azomethine ylides. / Nyerges, Miklós; Pintér, Áron; Virányi, A.; Blaskó, Gábor; Tőke, L.

In: Tetrahedron, Vol. 61, No. 34, 22.08.2005, p. 8199-8205.

Research output: Contribution to journalArticle

Nyerges, Miklós ; Pintér, Áron ; Virányi, A. ; Blaskó, Gábor ; Tőke, L. / Synthesis of pyrrolo[3,4-c]quinolines by 1,5-electrocyclisation of non-stabilised azomethine ylides. In: Tetrahedron. 2005 ; Vol. 61, No. 34. pp. 8199-8205.
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