Synthesis of pyrrolo[2,1-a]isoquinolines by a tandem 1,5- electrocyclisation-oxidation process

Judit Tóth, Andrea Nedves, András Dancsó, Gábor Blaskó, László Toke, Miklós Nyerges

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

A simple protocol for the convenient synthesis of 5,6-dihydropyrrolo[2,1-a] isoquinolines, utilising a one-pot, sequential azomethine ylide 1,5-electrocyclisation-oxidation process is described.

Original languageEnglish
Pages (from-to)1003-1014
Number of pages12
JournalSynthesis
Issue number7
DOIs
Publication statusPublished - Apr 3 2007

Keywords

  • Alkaloids
  • Azomethine ylides
  • Cycloaddition
  • Electrocyclic reaction
  • Pyrroles

ASJC Scopus subject areas

  • Catalysis
  • Organic Chemistry

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