Synthesis of polyfused heteroaromatics by palladium-catalyzed cross-coupling reaction

Géza Timári, G. Hajós, Z. Riedl, Mariann Béres, T. Soós, András Messmer, Salo Gronowitz

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

The palladium-catalyzed coupling of unsaturated halides or triflates with organostannanes (the Stille reaction) or with organo-boronic acids (the Suzuki reaction) has envolved as a powerful means of carbon-carbon bond formation. As an extention of our work on the synthesis and reactivity of positively charged bridge-head nitrogen containing fused azinium salts, we have been studying the formation of polyfused heteroaromatics with angular anellation pattern. The reaction of such positively charged salts with nucleophiles has proven to be a suitable tool for the preparation of heteroaryl dienes, which have been shown to be excellent intermediates for several ring closure reaction. A selection of results will be presented, including applications to natural product synthesis.

Original languageEnglish
Pages (from-to)236-241
Number of pages6
JournalMolecules
Volume1
Issue number10
DOIs
Publication statusPublished - Feb 1997

Fingerprint

cross coupling
Cross Reactions
Palladium
palladium
Carbon
Salts
Fused salts
Boronic Acids
Nucleophiles
synthesis
Biological Products
Nitrogen
Head
salts
carbon
nucleophiles
dienes
closures
halides
reactivity

Keywords

  • Azinium salt
  • Cross-coupling reaction
  • Furoquinolone
  • Review
  • Thienoisoquinoline

ASJC Scopus subject areas

  • Organic Chemistry

Cite this

Synthesis of polyfused heteroaromatics by palladium-catalyzed cross-coupling reaction. / Timári, Géza; Hajós, G.; Riedl, Z.; Béres, Mariann; Soós, T.; Messmer, András; Gronowitz, Salo.

In: Molecules, Vol. 1, No. 10, 02.1997, p. 236-241.

Research output: Contribution to journalArticle

Timári, Géza ; Hajós, G. ; Riedl, Z. ; Béres, Mariann ; Soós, T. ; Messmer, András ; Gronowitz, Salo. / Synthesis of polyfused heteroaromatics by palladium-catalyzed cross-coupling reaction. In: Molecules. 1997 ; Vol. 1, No. 10. pp. 236-241.
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