Synthesis of new thienopyridine derivatives by a reaction of 4-(Methylsulfanyl)-6,7-dihydrothieno[3,2-c]pyridine with amino acids

Mátyás Milen, Péter Ábrányi-Balogh, András Dancsõ, L. Drahos, G. Keglevich

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

New thienopyridine derivatives were synthesized by the reaction of 4-(methylsulfanyl)-6,7-dihydrothieno[3,2-c]pyridine (5) with amino acids. The use of β-amino acids led to thienopyridopyrimidone derivatives (9a-g). Using α-amino acids, such as glycine and racemic alanine under the same reaction conditions, compounds with two thienopyridine units were obtained. The structure of the novel compounds was confirmed by IR, 13C, and 1H NMR spectroscopy, as well as mass spectrometry, along with single crystal X-ray analysis.

Original languageEnglish
Pages (from-to)124-130
Number of pages7
JournalHeteroatom Chemistry
Volume24
Issue number2
DOIs
Publication statusPublished - Mar 2013

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Thienopyridines
Amino Acids
X ray analysis
Alanine
Glycine
Nuclear magnetic resonance spectroscopy
Mass spectrometry
Single crystals
Derivatives
pyridine

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Synthesis of new thienopyridine derivatives by a reaction of 4-(Methylsulfanyl)-6,7-dihydrothieno[3,2-c]pyridine with amino acids. / Milen, Mátyás; Ábrányi-Balogh, Péter; Dancsõ, András; Drahos, L.; Keglevich, G.

In: Heteroatom Chemistry, Vol. 24, No. 2, 03.2013, p. 124-130.

Research output: Contribution to journalArticle

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