Synthesis of new thienopyridine derivatives by [3+2]- and [2+2]-cycloaddition reactions

Mátyás Milen, Péter Ábrányi-Balogh, András Dancsó, G. Keglevich

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

The reaction of 6,7-dihydrothieno[3,2-c]pyridine derivatives with 1,3-dipoles, such as a nitrile oxides or nitrile imines, gave novel fused heterocycles. The Staudinger reaction of the starting material was also studied. This reaction was stereoselective and exclusively gave racemic cis-cycloadducts in which the thienopyridine core was fused with a β-lactam ring.

Original languageEnglish
Article numberSS-2012-T0593-OP
Pages (from-to)3447-3452
Number of pages6
JournalSynthesis
Volume44
Issue number22
DOIs
Publication statusPublished - 2012

Fingerprint

Thienopyridines
Nitriles
Cycloaddition
Pyridine
Derivatives
Lactams
Oxides
Imines

Keywords

  • cycloadditions
  • heterocycles
  • nitrile imines
  • nitrile oxides
  • Staudinger reactions

ASJC Scopus subject areas

  • Organic Chemistry
  • Catalysis

Cite this

Synthesis of new thienopyridine derivatives by [3+2]- and [2+2]-cycloaddition reactions. / Milen, Mátyás; Ábrányi-Balogh, Péter; Dancsó, András; Keglevich, G.

In: Synthesis, Vol. 44, No. 22, SS-2012-T0593-OP, 2012, p. 3447-3452.

Research output: Contribution to journalArticle

Milen, M, Ábrányi-Balogh, P, Dancsó, A & Keglevich, G 2012, 'Synthesis of new thienopyridine derivatives by [3+2]- and [2+2]-cycloaddition reactions', Synthesis, vol. 44, no. 22, SS-2012-T0593-OP, pp. 3447-3452. https://doi.org/10.1055/s-0032-1316794
Milen, Mátyás ; Ábrányi-Balogh, Péter ; Dancsó, András ; Keglevich, G. / Synthesis of new thienopyridine derivatives by [3+2]- and [2+2]-cycloaddition reactions. In: Synthesis. 2012 ; Vol. 44, No. 22. pp. 3447-3452.
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