Synthesis of new conformationally rigid paramagnetic α-amino acids

Mária Balog, Tamás Kálai, József Jeko, Zoltán Berente, Heinz Jürgen Steinhoff, Martin Engelhard, Kálmán Hideg

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20 Citations (Scopus)


A pyrroline nitroxide based cyclic tetrasubstituted α-amino acid and paramagnetic homoproline and their derivatives are described. Introduction of a new paramagnetic protecting group to follow the incorporation of an amino acid into peptides by EPR is also suggested.

Original languageEnglish
Pages (from-to)9213-9217
Number of pages5
JournalTetrahedron Letters
Issue number51
Publication statusPublished - Dec 15 2003



  • Amino acids
  • Nitroxides
  • Protecting group
  • TOAC

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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