Synthesis of lipid II phosphonate analogues

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Simple analogues of lipid II were synthesized from 3,4,6-tri-O-acetyl-2- acetamido-2-deoxy-1-thio-β-d-glucopyranose using conjugate addition onto ethylidene bisphosphonate and subsequent Wadsworth-Horner-Emmons reaction with long chain aliphatic aldehydes.

Original languageEnglish
Pages (from-to)1628-1632
Number of pages5
JournalCarbohydrate Research
Volume346
Issue number12
DOIs
Publication statusPublished - Sep 6 2011

    Fingerprint

Keywords

  • Conjugate addition
  • Lipid II analogues
  • Wadsworth-Horner-Emmons reaction

ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry
  • Organic Chemistry

Cite this