Synthesis of fluorous trialkyl phosphines with the complete exclusion of PH3

Gábor Vlád, Frank U. Richter, István T. Horváth

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

A novel synthetic protocol has been developed for the synthesis of fluorous tertiary phosphines excluding the use of hazardous PH3 and with control over the number of methylene spacers and the length of fluorous ponytails.

Original languageEnglish
Pages (from-to)8605-8608
Number of pages4
JournalTetrahedron Letters
Volume46
Issue number49
DOIs
Publication statusPublished - Dec 5 2005

Keywords

  • Fluorous
  • Phosphine oxides
  • Phosphines
  • Phosphonium salts
  • Radical addition

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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