Synthesis of ferrocenoyl amino acid derivatives via homogeneous catalytic aminocarbonylation

Árpád Kuik, Rita Skoda-Földes, János Balogh, László Kollár

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

Palladium-catalysed aminocarbonylation of iodoferrocene with amino acid esters as nucleophiles results in the selective formation of N-ferrocenoyl amino acid esters in the presence of Et3N as the base. At the same time, the use of DBU leads to the formation of new N-ferrocenylglyoxyl amino acid derivatives with reasonable selectivity. In the latter reactions two new side products, formed via acylation of DBU, were also isolated and characterised.

Original languageEnglish
Pages (from-to)3237-3242
Number of pages6
JournalJournal of Organometallic Chemistry
Volume690
Issue number13
DOIs
Publication statusPublished - Jul 1 2005

Keywords

  • Amino acids
  • Carbonylation
  • Ferrocene
  • Pd-catalysts
  • α-Ketoamides

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry
  • Materials Chemistry

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