Synthesis of enantiomerically enriched (R)- and (S)-benzofuranyl- and benzo[b]thiophenyl-1,2-ethanediols via enantiopure cyanohydrins as intermediates

László Csaba Bencze, Csaba Paizs, Monica Ioana Toşa, Elemér Vass, Florin Dan Irimie

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11 Citations (Scopus)

Abstract

The chemoenzymatic synthesis of highly enantiopure (R)- and (S)-benzofuranyl- and benzo[b]thiophenyl-cyanohydrins and their chemical transformation into the corresponding heteroaryl-1,2-ethanediols is described.

Original languageEnglish
Pages (from-to)443-450
Number of pages8
JournalTetrahedron Asymmetry
Volume21
Issue number4
DOIs
Publication statusPublished - Mar 16 2010

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ASJC Scopus subject areas

  • Catalysis
  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry

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