Synthesis of enantiomerically enriched (R)- and (S)-benzofuranyl- and benzo[b]thiophenyl-1,2-ethanediols via enantiopure cyanohydrins as intermediates

László Csaba Bencze, Csaba Paizs, Monica Ioana Toşa, E. Vass, Florin Dan Irimie

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

The chemoenzymatic synthesis of highly enantiopure (R)- and (S)-benzofuranyl- and benzo[b]thiophenyl-cyanohydrins and their chemical transformation into the corresponding heteroaryl-1,2-ethanediols is described.

Original languageEnglish
Pages (from-to)443-450
Number of pages8
JournalTetrahedron Asymmetry
Volume21
Issue number4
DOIs
Publication statusPublished - Mar 16 2010

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Ethylene Glycol
synthesis
cyanohydrin

ASJC Scopus subject areas

  • Organic Chemistry
  • Inorganic Chemistry
  • Physical and Theoretical Chemistry
  • Catalysis

Cite this

Synthesis of enantiomerically enriched (R)- and (S)-benzofuranyl- and benzo[b]thiophenyl-1,2-ethanediols via enantiopure cyanohydrins as intermediates. / Bencze, László Csaba; Paizs, Csaba; Toşa, Monica Ioana; Vass, E.; Irimie, Florin Dan.

In: Tetrahedron Asymmetry, Vol. 21, No. 4, 16.03.2010, p. 443-450.

Research output: Contribution to journalArticle

Bencze, László Csaba ; Paizs, Csaba ; Toşa, Monica Ioana ; Vass, E. ; Irimie, Florin Dan. / Synthesis of enantiomerically enriched (R)- and (S)-benzofuranyl- and benzo[b]thiophenyl-1,2-ethanediols via enantiopure cyanohydrins as intermediates. In: Tetrahedron Asymmetry. 2010 ; Vol. 21, No. 4. pp. 443-450.
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