Synthesis of E- and Z-o-methoxy-substituted 2,3-diphenyl propenoic acids and its methyl esters

K. Felföldi, Mária Sutyinszky, N. Nagy, I. Pálinkó

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

A series of stereoisomeric o-methoxy-substituted 2,3-diphenyl propenoic acids and their methyl esters have been synthesized. The E isomers were prepared by a modified Perkin condensation (substituted benzaldehyde, phenylacetic acid, Et3N/acetic anhydride). The difficult to access Z isomers were obtained conveniently in good yields when the appropriate coumarin derivatives were allowed to react with KOH and CH3I in DMSO.

Original languageEnglish
Pages (from-to)1543-1553
Number of pages11
JournalSynthetic Communications
Volume30
Issue number9
Publication statusPublished - 2000

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Isomers
Esters
Coumarins
Acids
Dimethyl Sulfoxide
Condensation
diphenyl
phenylacetic acid
acetic anhydride
benzaldehyde

ASJC Scopus subject areas

  • Organic Chemistry

Cite this

Synthesis of E- and Z-o-methoxy-substituted 2,3-diphenyl propenoic acids and its methyl esters. / Felföldi, K.; Sutyinszky, Mária; Nagy, N.; Pálinkó, I.

In: Synthetic Communications, Vol. 30, No. 9, 2000, p. 1543-1553.

Research output: Contribution to journalArticle

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