Synthesis of carboxylic acid derivatives of 2-pyrazolines

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

2-Pyrazolines 7-12 bearing a carboxylic acid ester or a carboxamide side-chain have been prepared by treatment of the appropriate chalcone derivatives 2-6 with hydrazine hydrate or phenylhydrazine in hot acetic acid. 1-(2-Carboxyphenyl)-2-pyrazolines 24-30 and 1-(4-carboxyphenyl)-2-pyrazolines 31-41 were synthesized by the reaction of chalcones with (2-carboxyphenyl) hydrazine and (4-carboxyphenyl)hydrazine in hot acetic acid. Structures of all new compounds have been elucidated by microanalyses, 1H-, 13C-NMR and IR spectroscopic measurements.

Original languageEnglish
Pages (from-to)134-145
Number of pages12
JournalArkivoc
Volume2007
Issue number1
Publication statusPublished - May 3 2007

Fingerprint

hydrazine
Carboxylic Acids
Derivatives
Acetic Acid
Bearings (structural)
Chalcones
Chalcone
Esters
Nuclear magnetic resonance

Keywords

  • 2-pyrazolines
  • Chalcones
  • Hydrazines

ASJC Scopus subject areas

  • Organic Chemistry

Cite this

Synthesis of carboxylic acid derivatives of 2-pyrazolines. / Lévai, A.; Jekó́, J.

In: Arkivoc, Vol. 2007, No. 1, 03.05.2007, p. 134-145.

Research output: Contribution to journalArticle

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