Synthesis of bis(phosphonatomethyl)-,bis(phosphinatomethyl)-, and bis(phosphinoxidomethyl)amines, as well as related ring bis(phosphine) platinum complexes

G. Keglevich, Anna Szekrényi, Áron Szö llosy, L. Drahos

Research output: Contribution to journalArticle

32 Citations (Scopus)

Abstract

The double Kabachnik-Fields condensation of primary amines with 2 equivalents of the other reagents (formaldehyde and a >P(O)H species, such as dialkyl phosphites, diphenylphosphine oxide, as well as the related dioxaphosphorine and oxaphosphorine derivatives) carried out under microwave conditions afforded the title products in 79-94% yields. The bis(phosphinoxidomethyl)amines were converted, after double deoxygenation, to the corresponding ring platinum complexes.

Original languageEnglish
Pages (from-to)2265-2272
Number of pages8
JournalSynthetic Communications
Volume41
Issue number15
DOIs
Publication statusPublished - 2011

Fingerprint

phosphine
Platinum
Amines
Phosphites
Formaldehyde
Condensation
Microwaves
Derivatives

Keywords

  • α-Aminophosphine oxides
  • α-aminophosphonates
  • Kabachnik-Fields reaction
  • Microwave
  • Ring platinum complexes

ASJC Scopus subject areas

  • Organic Chemistry

Cite this

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title = "Synthesis of bis(phosphonatomethyl)-,bis(phosphinatomethyl)-, and bis(phosphinoxidomethyl)amines, as well as related ring bis(phosphine) platinum complexes",
abstract = "The double Kabachnik-Fields condensation of primary amines with 2 equivalents of the other reagents (formaldehyde and a >P(O)H species, such as dialkyl phosphites, diphenylphosphine oxide, as well as the related dioxaphosphorine and oxaphosphorine derivatives) carried out under microwave conditions afforded the title products in 79-94{\%} yields. The bis(phosphinoxidomethyl)amines were converted, after double deoxygenation, to the corresponding ring platinum complexes.",
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author = "G. Keglevich and Anna Szekr{\'e}nyi and {Sz{\"o} llosy}, {\'A}ron and L. Drahos",
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T1 - Synthesis of bis(phosphonatomethyl)-,bis(phosphinatomethyl)-, and bis(phosphinoxidomethyl)amines, as well as related ring bis(phosphine) platinum complexes

AU - Keglevich, G.

AU - Szekrényi, Anna

AU - Szö llosy, Áron

AU - Drahos, L.

PY - 2011

Y1 - 2011

N2 - The double Kabachnik-Fields condensation of primary amines with 2 equivalents of the other reagents (formaldehyde and a >P(O)H species, such as dialkyl phosphites, diphenylphosphine oxide, as well as the related dioxaphosphorine and oxaphosphorine derivatives) carried out under microwave conditions afforded the title products in 79-94% yields. The bis(phosphinoxidomethyl)amines were converted, after double deoxygenation, to the corresponding ring platinum complexes.

AB - The double Kabachnik-Fields condensation of primary amines with 2 equivalents of the other reagents (formaldehyde and a >P(O)H species, such as dialkyl phosphites, diphenylphosphine oxide, as well as the related dioxaphosphorine and oxaphosphorine derivatives) carried out under microwave conditions afforded the title products in 79-94% yields. The bis(phosphinoxidomethyl)amines were converted, after double deoxygenation, to the corresponding ring platinum complexes.

KW - α-Aminophosphine oxides

KW - α-aminophosphonates

KW - Kabachnik-Fields reaction

KW - Microwave

KW - Ring platinum complexes

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