Synthesis of azasteroids and D-homosteroids by intramolecular cyclization reactions of steroid arylimines

J. Wölfling, E. Frank, G. Schneider, Maria Teresa Bes, Lutz F. Tietze

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

Intramolecular Lewis acid-catalyzed cyclization reactions of steroid aryliminium salts 4a-e obtained from the secoestrone aldehyde 2 yield either the tetrahydroquinoline derivatives of estrone methyl ether 8a-d or the N-arylamino-D-homosteroids 7a-f, depending on the nature of the substituent R at the aniline moiety in 4.

Original languageEnglish
Pages (from-to)1205-1206
Number of pages2
JournalSynlett
Issue number11
Publication statusPublished - Nov 1998

Fingerprint

Homosteroids
Azasteroids
Methyl Ethers
Lewis Acids
Estrone
Cyclization
Aldehydes
Salts
Steroids
Derivatives
aniline
1,2,3,4-tetrahydroquinoline

ASJC Scopus subject areas

  • Organic Chemistry

Cite this

Synthesis of azasteroids and D-homosteroids by intramolecular cyclization reactions of steroid arylimines. / Wölfling, J.; Frank, E.; Schneider, G.; Bes, Maria Teresa; Tietze, Lutz F.

In: Synlett, No. 11, 11.1998, p. 1205-1206.

Research output: Contribution to journalArticle

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