Synthesis of alicyclic trans-β-amino acids from cis-β- hydroxycycloalkane-carboxylates

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10 Citations (Scopus)

Abstract

A simple and efficient method is described for the preparation of both racemic and enantiopure trans-β-amino acids with a cycloheptane or cyclooctane skeleton, starting from racemic and enantiopure ethyl cis-2-hydroxycarboxylates.

Original languageEnglish
Pages (from-to)1265-1268
Number of pages4
JournalSynthesis
Issue number8
DOIs
Publication statusPublished - May 20 2005

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Cycloheptanes
Amino acids
Amino Acids
cyclooctane

Keywords

  • Amino acids
  • Antifungal agents
  • Chiral resolution
  • Drugs
  • Natural products

ASJC Scopus subject areas

  • Organic Chemistry

Cite this

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title = "Synthesis of alicyclic trans-β-amino acids from cis-β- hydroxycycloalkane-carboxylates",
abstract = "A simple and efficient method is described for the preparation of both racemic and enantiopure trans-β-amino acids with a cycloheptane or cyclooctane skeleton, starting from racemic and enantiopure ethyl cis-2-hydroxycarboxylates.",
keywords = "Amino acids, Antifungal agents, Chiral resolution, Drugs, Natural products",
author = "L. Kiss and E. Forr{\'o} and G. Bern{\'a}th and F. F{\"u}l{\"o}p",
year = "2005",
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T1 - Synthesis of alicyclic trans-β-amino acids from cis-β- hydroxycycloalkane-carboxylates

AU - Kiss, L.

AU - Forró, E.

AU - Bernáth, G.

AU - Fülöp, F.

PY - 2005/5/20

Y1 - 2005/5/20

N2 - A simple and efficient method is described for the preparation of both racemic and enantiopure trans-β-amino acids with a cycloheptane or cyclooctane skeleton, starting from racemic and enantiopure ethyl cis-2-hydroxycarboxylates.

AB - A simple and efficient method is described for the preparation of both racemic and enantiopure trans-β-amino acids with a cycloheptane or cyclooctane skeleton, starting from racemic and enantiopure ethyl cis-2-hydroxycarboxylates.

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KW - Antifungal agents

KW - Chiral resolution

KW - Drugs

KW - Natural products

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