Synthesis of alicyclic trans-β-amino acids from cis-β- hydroxycycloalkane-carboxylates

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Abstract

A simple and efficient method is described for the preparation of both racemic and enantiopure trans-β-amino acids with a cycloheptane or cyclooctane skeleton, starting from racemic and enantiopure ethyl cis-2-hydroxycarboxylates.

Original languageEnglish
Pages (from-to)1265-1268
Number of pages4
JournalSynthesis
Issue number8
DOIs
Publication statusPublished - May 20 2005

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Keywords

  • Amino acids
  • Antifungal agents
  • Chiral resolution
  • Drugs
  • Natural products

ASJC Scopus subject areas

  • Catalysis
  • Organic Chemistry

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