Synthesis of a pericosine analogue with a bicyclo[2.2.2]octene skeleton

Zsolt Fejes, Attila Mándi, I. Komáromi, A. Bényei, Lieve Naesens, Ferenc Fenyvesi, László Szilágyi, P. Herczegh

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

A new analogue of the antitumor pericosines possessing a bicyclo[2.2.2]octene skeleton has been synthesized from methyl gallate using oxidative dearomatization and regio- and diastereoselective Diels-Alder reaction as the key steps.

Original languageEnglish
Pages (from-to)8171-8175
Number of pages5
JournalTetrahedron
Volume65
Issue number39
DOIs
Publication statusPublished - Sep 26 2009

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Cycloaddition Reaction
Skeleton
methyl gallate

Keywords

  • Bicyclo[2.2.2]octene
  • Diels-Alder cycloaddition
  • Houk rule violation
  • Oxidative dearomatization

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

Synthesis of a pericosine analogue with a bicyclo[2.2.2]octene skeleton. / Fejes, Zsolt; Mándi, Attila; Komáromi, I.; Bényei, A.; Naesens, Lieve; Fenyvesi, Ferenc; Szilágyi, László; Herczegh, P.

In: Tetrahedron, Vol. 65, No. 39, 26.09.2009, p. 8171-8175.

Research output: Contribution to journalArticle

Fejes, Zsolt ; Mándi, Attila ; Komáromi, I. ; Bényei, A. ; Naesens, Lieve ; Fenyvesi, Ferenc ; Szilágyi, László ; Herczegh, P. / Synthesis of a pericosine analogue with a bicyclo[2.2.2]octene skeleton. In: Tetrahedron. 2009 ; Vol. 65, No. 39. pp. 8171-8175.
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AU - Fenyvesi, Ferenc

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